It has about 1100 residents and it is located on the west side of the island, 65km away from Mytilini.

Warm hospitality and a wealth of cultural activities are the elements that characterize the village of Mesotopos most. This is where the successful Women’s Association of Agricultural Tourism is based, founded in 1998 and supplying visitors with traditional products of exceptional quality. The village is famous for its traditional carnival, which sees the revival of old dionysian rituals.